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  2. Multiple myeloma - Wikipedia

    en.wikipedia.org/wiki/Multiple_myeloma

    MGUS is a relatively stable condition afflicting 3% of people aged 50 and 5% of people aged 70; it progresses to multiple myeloma at a rate of 0.5–1% cases per year; smoldering multiple myeloma does so at a rate of 10% per year for the first 5 years, but then falls off sharply to 3% per year for the next 5 years and thereafter to 1% per year.

  3. Plasmacytoma - Wikipedia

    en.wikipedia.org/wiki/Plasmacytoma

    Most cases of SPB progress to multiple myeloma within 2–4 years of diagnosis, but the overall median survival for SPB is 7–12 years. 30–50% of extramedullary plasmacytoma cases progress to multiple myeloma with a median time of 1.5–2.5 years. 15–45% of SPB and 50–65% of extramedullary plasmacytoma are disease free after 10 years. [3]

  4. Smouldering myeloma - Wikipedia

    en.wikipedia.org/wiki/Smouldering_myeloma

    Smouldering myeloma is a disease classified as intermediate in a spectrum of step-wise progressive diseases termed plasma cell dyscrasias.In this spectrum of diseases, a clone of plasma cells secreting monoclonal paraprotein (also termed myeloma protein or M protein) causes the relatively benign disease of monoclonal gammopathy of undetermined significance.

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    The five-year survival rate for multiple myeloma patients ranges from 40% to 82%, per the Cleveland Clinic, which notes that it affects about seven out of 100,000 people a year and that "some ...

  6. Plasma cell leukemia - Wikipedia

    en.wikipedia.org/wiki/Plasma_cell_leukemia

    Secondary PCL (sPCL) is diagnosed in 1-4% of patients known to have had multiple myeloma for a median time of ~21 months. It is the terminal phase of these patients' myeloma disease. sPCL patients typically are highly symptomatic due to extensive disease with malignant plasma cell infiltrations in, and failures of, not only the bone marrow but also other organs.

  7. Plasma cell dyscrasias - Wikipedia

    en.wikipedia.org/wiki/Plasma_cell_dyscrasias

    In hematology, plasma cell dyscrasias (also termed plasma cell disorders and plasma cell proliferative diseases) are a spectrum of progressively more severe monoclonal gammopathies in which a clone or multiple clones of pre-malignant or malignant plasma cells (sometimes in association with lymphoplasmacytoid cells or B lymphocytes) over-produce and secrete into the blood stream a myeloma ...

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