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The disease can affect humans as well as animals such as dogs. The condition is treatable and need not shorten the animal's life span or interfere with the quality of life. [1] If left untreated, the condition can lead to cataracts, increasing weakness in the legs (neuropathy), malnutrition, ketoacidosis, dehydration, and death. [2]
A study of 66 dogs with Cushing's found 91% of dogs to have either polyuria or polydipsia, 79% to have polyphagia, and 77% to have alopecia. [ 4 ] Signs of ectopic adrenocorticotropic hormone secretion that accompany the rapidly progressing physical changes are high plasma levels of adrenocorticotropic hormones and cortisol alongside hypokalaemia .
Obese dogs are more likely to develop urinary incontinence, may have difficulty breathing, and overall have a poorer quality of life compared to non-obese dogs, [17] as well as having a lower life expectancy. [1] Obese cats have an increased risk of diseases affecting the mouth and urinary tract. [17]
Auto-brewery syndrome (ABS) (also known as gut fermentation syndrome, endogenous ethanol fermentation or drunkenness disease) is a condition characterized by the fermentation of ingested carbohydrates in the gastrointestinal tract of the body caused by bacteria or fungi. [1]
Physical symptoms generally include coarse or rough facial features (including a flat nasal bridge, thick lips, and enlarged mouth and tongue), short stature with disproportionately short trunk , dysplasia (abnormal bone size and/or shape) and other skeletal irregularities, thickened skin, enlarged organs such as liver (hepatomegaly) or spleen ...
Toxic in humans, dogs, and cats alike. Extremely dangerous to dogs (and children) due to its sweet taste. The antifreeze itself is not toxic, but is metabolized via the liver to the toxins glycolate and oxalate, which cause intoxication and vomiting, metabolic acidosis, and finally acute kidney failure leading to seizures and death. By the time ...
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Decreasing caloric intake by 20-30%, while fulfilling nutrient requirements, has been found to remedy diseases of aging, including cancer, cardiovascular disease, dementia, and diabetes in humans, and result in an average loss of 7.9 kilograms (17 lb) in body weight, but because of the long lifespan of humans, evidence that calorie restriction ...