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Endoscopic examination most often reveals a single polyp or rarely multiple polyps, a mucosal ulcer, or a mucosal nodule. Diagnosis is passed on biopsy of the lesions showing a histology typical of EMZL, e.g. diffuse infiltrates composed of small to medium-sized lymphocytes that may show morphological features of monocytes and/or plasma cells.
The lesions are usually ulcers with a ragged, thickened mucosal pattern on contrast radiographs. The diagnosis is typically made by biopsy at the time of endoscopy . Several endoscopic findings have been reported, including solitary ulcers, thickened gastric folds, mass lesions and nodules.
Pneumatosis is the abnormal presence of air or other gas within tissues. [1] In the lungs, emphysema involves enlargement of the distal airspaces, [2] and is a major feature of chronic obstructive pulmonary disease (COPD). Other pneumatoses in the lungs are focal (localized) blebs and bullae, pulmonary cysts and cavities.
The mucosa-associated lymphoid tissue (MALT), also called mucosa-associated lymphatic tissue, is a diffuse system of small concentrations of lymphoid tissue found in various submucosal membrane sites of the body, such as the gastrointestinal tract, nasopharynx, thyroid, breast, lung, salivary glands, eye, and skin.
Localized, or specific lymphadenopathies should be evaluated for etiologies that are associated with lymphatic drainage patterns. During a complete lymphatic physical examination, generalized lymphadenopathy may or may not be ruled out. [6] BCL2 protein expression is usually absent in follicular hyperplasia but prominent in follicular lymphomas.
The mucosal surface is usually intact except for areas of ulceration, which are generally present in 50% of GISTs. Ulcerations fill with barium causing a bull's eye or target lesion appearance. In contrast-enhanced CT , small GISTs are seen as smooth, sharply defined intramural masses with homogeneous attenuation.
A solitary pulmonary nodule (SPN) or coin lesion, [1] is a mass in the lung smaller than three centimeters in diameter. A pulmonary micronodule has a diameter of less than three millimetres. [2] There may also be multiple nodules. One or more lung nodules can be an incidental finding found in up to 0.2% of chest X-rays [3] and around 1% of CT ...
Peyer's patches (or aggregated lymphoid nodules) are organized lymphoid follicles, named after the 17th-century Swiss anatomist Johann Conrad Peyer. [1] They are an important part of gut associated lymphoid tissue usually found in humans in the lowest portion of the small intestine, mainly in the distal jejunum and the ileum, but also could be detected in the duodenum.