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Given the widespread impacts of Alzheimer's disease, both basic-science and health funders in many countries support Alzheimer's research at large scales. For example, the US National Institutes of Health program for Alzheimer's research, the National Plan to Address Alzheimer’s Disease, has a budget of US$3.98 billion for fiscal year 2026 ...
In a 2006 survey of patients with long-term care insurance, the direct and indirect costs of caring for an Alzheimer's disease patient averaged $77,500 per year in the United States. [3] Caregivers themselves are subject to an increased incidence of depression, anxiety, and, in some cases, physical health issues.
A 2012 report by the Alzheimer's Association states that 15 million of those family caregivers are caring for a person with Alzheimer's disease or another dementia. [3] The value of the voluntary, "unpaid" caregiving service provided by caregivers was estimated at $310 billion in 2006 — almost twice as much as was actually spent on home care ...
“The APOE-e4 allele is the most important for Alzheimer’s disease risk,” she continued.“About 25% of people in the U.S. have at least one APOE-e4 allele and about 5% have two copies of it ...
Alzheimer’s usually is a disease of people over age 65 and while simply getting older is the main risk, the APOE gene has long been known to play some role. It comes in three main varieties.
It is an uncommon form of Alzheimer's, accounting for only 5–10% of all Alzheimer's cases. About 60% have a positive family history of Alzheimer's and 13% of them are inherited in an autosomal dominant manner. Most cases of early-onset Alzheimer's share the same traits as the "late-onset" form and are not caused by known genetic mutations.
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