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Nonoxynol-9 is a common ingredient of most vaginal and anal lubricants due to its spermicidal properties. A 2004 study found that over a six-month period, the typical-use failure rates for five nonoxynol-9 vaginal contraceptives (film, suppository, and gels at three different concentrations) ranged from 10% to 20%.
Side effects if contact occurs may include skin irritation and chemical burns to the eye. [2] They may also cause corrosion and therefore may require being rinsed off. [ 3 ] Specific compounds in this family include sodium hypochlorite , monochloramine , halazone , chlorine dioxide , and sodium dichloroisocyanurate .
Effects on animals Effects on animals p-Chlorocresol has low to moderate acute oral toxicity in rats and mice, with a median lethal dose (LD50) of 1830 mg/kg in male Wistar rats. [25] It has also been shown to be corrosive to the skin of New Zealand White rabbits when applied dermally, and an irritant to rabbit eyes. [ 26 ]
That changed in 1980, and since then, tons of other brands of lubricant have flooded the market. Many people having sex (including solo sex) know that lube is a must-have in their pleasure tool kit.
Aqueous or solvent cleaning both have accepted methods to dispose of the "sludge" created. It has been reported that talcum powder can be used as an absorbent of cosmoline by packing the powder around the item to be cleaned and applying sufficient heat to melt the solid film, allowing the compound to be wicked from the coated surface into the ...
Benzalkonium chloride has been in common use as a pharmaceutical preservative and antimicrobial since the 1940s. While early studies confirmed the corrosive and irritant properties of benzalkonium chloride, investigations into the adverse effects of, and disease states linked to, benzalkonium chloride have only surfaced during the past 30 years.
Chloroxylenol, also known as para-chloro-meta-xylenol (PCMX), is a chlorine substituted phenol with a white to off-white appearance and a phenolic odor.. The discovery of chloroxylenol was the result of efforts to produce improved antiseptics that began at the end of the 1800s, when scientists gradually realized that more substituted and more lipophilic phenols are less toxic, less irritant ...
It acts primarily as a stool lubricant, and is thus not associated with abdominal cramps, diarrhea, flatulence, disturbances in electrolytes, or tolerance over long periods of usage, side effects that osmotic and stimulant laxatives often engender (however, some literature suggests that these may still occur).