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Coalescent theory is a model of how alleles sampled from a population may have originated from a common ancestor. In the simplest case, coalescent theory assumes no recombination , no natural selection , and no gene flow or population structure , meaning that each variant is equally likely to have been passed from one generation to the next.
Sir John Frank Charles Kingman FRS [4] (born 28 August 1939) [5] is a British mathematician. [2] [6] He served as N. M. Rothschild and Sons Professor of Mathematical Sciences and Director of the Isaac Newton Institute at the University of Cambridge from 2001 until 2006, [1] [5] [7] when he was succeeded by David Wallace.
Coalescence (genetics) or the coalescent theory, the merging of genetic lineages backwards to a most recent common ancestor, in other words a model of how alleles sampled from a population may have originated from a common ancestor
This estimate is based on coalescent theory. Watterson's estimator is commonly used for its simplicity. When its assumptions are met, the estimator is unbiased and the variance of the estimator decreases with increasing sample size or recombination rate. However, the estimator can be biased by population structure.
Another important branch of population genetics that led to the extensive development of coalescent theory is phylogenetics. Phylogenetics is an area that deals with the reconstruction and analysis of phylogenetic (evolutionary) trees and networks based on inherited characteristics [ 45 ] Traditional population genetic models deal with alleles ...
Coalescent theory, a retrospective model of population genetics; Crown group; Genealogy, the study of families and the tracing of their lineages and history; Genetic distance, the genetic divergence between species or between populations within a species; Lowest common ancestor, an analogous concept in graph theory and computer science
Multispecies Coalescent Process is a stochastic process model that describes the genealogical relationships for a sample of DNA sequences taken from several species. [ 1 ] [ 2 ] It represents the application of coalescent theory to the case of multiple species.
Representation of the coalescence of two droplets, bubbles, or particles to form a single entity. Coalescence is the process by which two or more droplets, bubbles, or particles merge during contact to form a single daughter droplet, bubble, or particle.