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A 2006 clinical trial found no statistically significant change in hypertrophic scar appearance from products of this type compared to the standard petrolatum emollient. [6] According to a 2011 Los Angeles Times article, "there were just two randomized comparison trials of Mederma, with a combined total of 38 participants. Neither trial found ...
This process can take many hours, and often requires repeated removal of scabs for best visibility of the scars. [6] Packing An inert material such as clay or ash is packed into the wound; massive hypertrophic scars are formed during healing as the wound pushes out the substance that had been inserted into the wound. [18]
Nepidermin (INN proposed), [2] also known as recombinant human epidermal growth factor (rhEGF), is a recombinant form of human epidermal growth factor (EGF) and a cicatrizant (a drug that promotes wound healing through formation of scar tissue).
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Maggot therapy (also known as larval therapy) is a type of biotherapy involving the introduction of live, disinfected maggots (fly larvae) into non-healing skin and soft-tissue wounds of a human or other animal for the purpose of cleaning out the necrotic (dead) tissue within a wound (debridement), and disinfection.
Merbromin's best-known use is as a topical antiseptic to treat minor wounds, burns, and scratches. [3] It is also used in the antisepsis of the umbilical cord, [4] and the antisepsis of wounds with inhibited scar formation, such as neuropathic ulcers and diabetic foot sores. [5]