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High grade squamous intraepithelial lesion (HGSIL or HSIL) Squamous cell carcinoma; Atypical Glandular Cells not otherwise specified (AGC-NOS) Atypical Glandular Cells, suspicious for AIS or cancer (AGC-neoplastic) Adenocarcinoma in situ (AIS) The results are calculated differently following a Pap smear of the cervix. [citation needed]
It can be treated by using methods that remove the abnormal cells, allowing normal cells to grow in their place. [1] In the Bethesda system, the cytology can be graded as LSIL (low-grade squamous intraepithelial lesion) or HSIL (high-grade squamous intraepithelial lesion). [citation needed]
Dysplasia is the earliest form of precancerous lesion which pathologists can recognize in a pap smear or in a biopsy. Dysplasia can be low grade or high grade. The risk of low-grade dysplasia transforming into high-grade dysplasia, and eventually cancer, is low. Treatment is usually straightforward.
For decades, a Pap smear has been the standard way to detect cervical cancer. The uncomfortable and, for some, painful procedure entails using a small brush or spatula to lightly scrape the cervix ...
ThinPrep pap smear with group of normal cervical cells on left and HPV-infected cells showing features typical of koilocytes: enlarged (x2 or x3) nuclei and hyperchromasia. A koilocyte is a squamous epithelial cell that has undergone a number of structural changes, which occur as a result of infection of the cell by human papillomavirus (HPV). [1]
Currently, the pap smear — in which cells taken from the cervix are examined by a doctor “for cervical cancer or cell changes,” per the National Cancer Institute — is the recommended ...
Papanicolaou stain showing a low-grade squamous intraepithelial lesion (LSIL) from a Pap test. Cell nuclei stained blue.. Papanicolaou stain (also Papanicolaou's stain and Pap stain) is a multichromatic (multicolored) cytological staining technique developed by George Papanicolaou in 1942.
In a pap smear, a gynecologist uses a speculum to open the walls of the vagina, and then uses an instrument to collect cells from the cervix. As the Mayo Clinic notes, it “may feel uncomfortable.