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The literature examining the pharmacological treatment of rapid cycling is sparse and there is no clear consensus with respect to its optimal pharmacological management. [118] "Ultra rapid" and "ultradian" have been applied to faster-cycling types of bipolar disorder. [119]
Mixed features (as well as rapid cycling) are more common in women with bipolar disorder. Suicidal thoughts or behaviors. Research suggests that bipolar poses the highest risk of suicide of any ...
Bipolar disorder is often a lifelong condition, and patients should be followed up regularly for relapse prevention. [27] Although BP-II is thought to be less severe than BP-I in regard to symptom intensity, BP-II is associated with higher frequencies of rapid cycling and depressive episodes. [28]
He then went to New York for eight years to work with Ronald R. Fieve on studies of Bipolar disorder and the emerging Lithium treatment, and developed the concept of 'rapid cycling' for bipolar disorder which was found to show less response to Lithium (he credits Canadian scientist Harvey Stancer for first noticing the connection a year prior).
Furthermore, preliminary research into the use of thyroid augmentation in patients with refractory and rapid-cycling bipolar disorder has been positive, showing a slowing in cycle frequency and reduction in symptoms. Most studies have been conducted on an open-label basis.
For Bipolar I Disorder 296.40 (most recent episode hypomanic) and 296.4x (most recent episode manic), the proposed revision includes the following specifiers: with psychotic features, with mixed features, with catatonic features, with rapid cycling, with anxiety (mild to severe), with suicide risk severity, with seasonal pattern, and with ...