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Trolamine salicylate (Aspercreme, Aspergel) is an organic compound with the chemical formula [HN(CH 2 CH 2 OH) 3] + C 6 H 4 (OH)(COO −).It is a salt of triethanolamine and salicylic acid, i.e. the compound consists of protonated triethanolamine and the conjugate base of salicylic acid, salicate.
Sodium salicylate is a sodium salt of salicylic acid. It can be prepared from sodium phenolate and carbon dioxide under higher temperature and pressure. Historically, it has been synthesized by refluxing methyl salicylate ( wintergreen oil) with an excess of sodium hydroxide .
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Repeated doses of activated charcoal have been proposed to be beneficial in cases of salicylate poisoning, [18] especially in ingestion of enteric coated and extended release salicylic acid formulations which are able to remain in the gastrointestinal (GI) tract for longer periods of time. [9]