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SAAM is treated by stopping the offending statin medication and taking immunosuppressive medications. [7] In rare cases, affected people spontaneously improve after just stopping the implicated statin. [3] However, most cases mandate the use of immunosuppressive medication. [8] Corticosteroids are considered first-line treatment.
Using PREVENT to calculate the 10-year risk for developing heart disease, the researchers determined that some 40% fewer people would have met the criteria for a statin prescription.
Atorvastatin is a statin medication used to prevent cardiovascular disease in those at high risk and to treat abnormal lipid levels. [4] For the prevention of cardiovascular disease, statins are a first-line treatment. [4] It is taken by mouth. [4] Common side effects include joint pain, diarrhea, heartburn, nausea, and muscle pains. [4]
The Scandinavian Simvastatin Survival Study (also known as the 4S study), was a multicentre, randomized, double-blind, placebo-controlled clinical trial, which provided the initial data that supported the use of the cholesterol-lowering drug, simvastatin, in people with a moderately raised cholesterol and coronary heart disease (CHD); that is people who had previously had a heart attack or angina.
[5] [6] [7] The study's authors estimated that the number needed to treat with rosuvastatin to prevent one cardiovascular event was 95 over two years, extrapolated to 25 over five years. The trial was stopped early, after just 1.9 years median duration, by the study's Independent Data Monitoring Board, because the interim results met the study ...
The data, published in the journal JAMA, showed patients who were obese and without diabetes experienced a 14% weight regain nearly a year after they switched to a placebo from an eight-month ...
Extreme hunger is common after people stop taking GLP-1 drugs like Ozempic and Wegovy, but health experts say these simple tips can help you successfully manage it and maintain a healthy weight.
Medication discontinuation is an important medical practice that may be motivated by a number of reasons: [4] [3] Reducing polypharmacy; Reducing health expenditure; Improving quality of life by ceasing medications with potential adverse effects or where the indication for a medical treatment may have changed