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  2. Levodopa - Wikipedia

    en.wikipedia.org/wiki/Levodopa

    However, when consumed as a botanical extract, for example from M pruriens supplements, a peripheral DOPA decarboxylase inhibitor is not present. [ 8 ] Inbrija (previously known as CVT-301) is an inhaled powder formulation of levodopa indicated for the intermittent treatment of "off episodes" in patients with Parkinson's disease currently ...

  3. L-DOPA - Wikipedia

    en.wikipedia.org/wiki/L-DOPA

    l-DOPA, also known as l-3,4-dihydroxyphenylalanine and used medically as levodopa, is made and used as part of the normal biology of some plants [2] and animals, including humans. Humans, as well as a portion of the other animals that utilize l -DOPA, make it via biosynthesis from the amino acid l -tyrosine .

  4. Droxidopa - Wikipedia

    en.wikipedia.org/wiki/Droxidopa

    Droxidopa, also known as (–)-threo-3-(3,4-dihydroxyphenyl)-L-serine (L-DOPS), is a substituted phenethylamine and is chemically analogous to levodopa (L-3,4-dihydroxyphenylalanine; L-DOPA). Whereas levodopa functions as a precursor and prodrug to dopamine , droxidopa is a precursor and prodrug of norepinephrine .

  5. DopAmide - Wikipedia

    en.wikipedia.org/wiki/DopAmide

    DopAmide, or L-DopAmide, is a synthetic levodopa (L-DOPA) analogue that can serve as a levodopa and dopamine prodrug and is of potential interest in the treatment of Parkinson's disease. [ 1 ] [ 2 ] [ 3 ] DopAmide has an amide rather than the carboxyl group of L -DOPA, [ 2 ] [ 3 ] which imparts greater water solubility .

  6. XP-21279 - Wikipedia

    en.wikipedia.org/wiki/XP-21279

    XP-21279 is a sustained-release levodopa (L-DOPA) prodrug and hence a dopamine precursor and non-selective dopamine receptor agonist which was under development for the treatment of Parkinson's disease. [4] [1] [3] It is taken by mouth. [1] [2] [3]

  7. Benserazide - Wikipedia

    en.wikipedia.org/wiki/Benserazide

    Benserazide is a peripherally acting aromatic L-amino acid decarboxylase or DOPA decarboxylase inhibitor, which is unable to cross the blood–brain barrier. [1] It is on the World Health Organization's List of Essential Medicines. [2]