Ad
related to: complex 1 mitochondria definition
Search results
Results From The WOW.Com Content Network
Respiratory complex I, EC 7.1.1.2 (also known as NADH:ubiquinone oxidoreductase, Type I NADH dehydrogenase and mitochondrial complex I) is the first large protein complex of the respiratory chains of many organisms from bacteria to humans.
The most common supercomplexes observed are Complex I/III, Complex I/III/IV, and Complex III/IV. Most of Complex II is found in a free-floating form in both plant and animal mitochondria. Complex V can be found co-migrating as a dimer with other supercomplexes, but scarcely as part of the supercomplex unit. [1]
The structure is known in detail only from a bacterium; [20] [21] in most organisms the complex resembles a boot with a large "ball" poking out from the membrane into the mitochondrion. [ 22 ] [ 23 ] The genes that encode the individual proteins are contained in both the cell nucleus and the mitochondrial genome , as is the case for many ...
In mitochondria, the terminal membrane complex (Complex IV) is cytochrome oxidase, which oxidizes the cytochrome. Aerobic bacteria use a number of differet terminal oxidases. For example, E. coli (a facultative anaerobe) does not have a cytochrome oxidase or a bc 1 complex. Under aerobic conditions, it uses two different terminal quinol ...
A mitochondrion (pl. mitochondria) is an organelle found in the cells of most eukaryotes, such as animals, plants and fungi. Mitochondria have a double membrane structure and use aerobic respiration to generate adenosine triphosphate (ATP), which is used throughout the cell as a source of chemical energy. [2]
In the mitochondrion, the matrix is the space within the inner membrane. The word "matrix" stems from the fact that this space is viscous, compared to the relatively aqueous cytoplasm. The mitochondrial matrix contains the mitochondrial DNA, ribosomes, soluble enzymes, small organic molecules, nucleotide cofactors, and inorganic ions. [1]
The enzyme cytochrome c oxidase or Complex IV (was EC 1.9.3.1, now reclassified as a translocase EC 7.1.1.9) is a large transmembrane protein complex found in bacteria, archaea, and the mitochondria of eukaryotes. [1] It is the last enzyme in the respiratory electron transport chain of cells located in the membrane.
[1] [2] [3] Generation of mitochondrial ROS mainly takes place at the electron transport chain located on the inner mitochondrial membrane during the process of oxidative phosphorylation. Leakage of electrons at complex I and complex III from electron transport chains leads to partial reduction of oxygen to form superoxide.