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In comics studies, sequential art is a term proposed by comics artist Will Eisner [1] to describe art forms that use images deployed in a specific order for the purpose of graphic storytelling [2] (i.e., narration of graphic stories) [3] or conveying information. [2] The best-known example of sequential art is comics. [4]
Sequence alignment can also reveal conserved domains and motifs. One motivation for local alignment is the difficulty of obtaining correct alignments in regions of low similarity between distantly related biological sequences, because mutations have added too much 'noise' over evolutionary time to allow for a meaningful comparison of those regions.
In bioinformatics, a sequence alignment is a way of arranging the sequences of DNA, RNA, or protein to identify regions of similarity that may be a consequence of functional, structural, or evolutionary relationships between the sequences. [1] Aligned sequences of nucleotide or amino acid residues are typically represented as rows within a matrix.
For example, audio alignment refers to the task of temporally aligning two different audio recordings of a piece of music. Similarly, the goal of score–audio alignment is to coordinate note events given in the score representation with audio data. In the offline scenario, the two data streams to be aligned are known prior to the actual alignment.
A global alignment performs an end-to-end alignment of the query sequence with the reference sequence. Ideally, this alignment technique is most suitable for closely related sequences of similar lengths. The Needleman-Wunsch algorithm is a dynamic programming technique used to conduct global alignment. Essentially, the algorithm divides the ...
In computer science, Hirschberg's algorithm, named after its inventor, Dan Hirschberg, is a dynamic programming algorithm that finds the optimal sequence alignment between two strings. Optimality is measured with the Levenshtein distance , defined to be the sum of the costs of insertions, replacements, deletions, and null actions needed to ...
A false sequence is a literal repetition of the beginning of a figure and stating the rest in sequence: [1] J.S. Bach Prelude from Cello Suite in G J.S. Bach Prelude from Cello Suite in G, BWV 1007. A modulating sequence is a sequence that leads from one tonal center to the next, with each segment technically being in a different key in some ...
The fourth is a great example of how interactive graphical tools enable a worker involved in sequence analysis to conveniently execute a variety if different computational tools to explore an alignment's phylogenetic implications; or, to predict the structure and functional properties of a specific sequence, e.g., comparative modelling.