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Creutzfeldt–Jakob disease is a rapidly progressive prion disease that typically causes dementia that worsens over weeks to months. Prions are disease-causing pathogens created from abnormal proteins.
In populations with a rapidly progressive dementia (early in the disease process), MRI has a sensitivity of 91% and specificity of 97% for diagnosing CJD. [43] The MRI changes characteristic of CJD may also be seen in the immediate aftermath (hours after the event) of autoimmune encephalitis or focal seizures. [36]
Pure LATE typically manifests as a slow, progressive decline in memory and other cognitive functions, which distinguishes it from more rapidly progressing forms of dementia. [65] [56] However, the rate of progression can vary widely among individuals. Early stages may involve subtle memory impairments that gradually worsen.
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Russell listed symptoms such as "rapidly progressing dementia", unusual weight loss, "tightening of the muscles", uncoordinated gait, and muscle atrophy. [ 47 ] Based on the memo, the CBC reported that in 2019, the CJDSS had identified a cluster of eleven cases in New Brunswick, with "some common symptoms and similar potential diagnostic ...
Older women have a higher overall risk of developing dementia in their lifetime than older men – about 48% compared with 35%, the new research estimates – but much of that difference is due to ...
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