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In the normal menstrual cycle, estradiol levels measure typically <50 pg/mL at menstruation, rise with follicular development (peak: 200 pg/mL), drop briefly at ovulation, and rise again during the luteal phase for a second peak. At the end of the luteal phase, estradiol levels drop to their menstrual levels unless there is a pregnancy.
Estradiol is an estrogen, or an agonist of the nuclear estrogen receptors (ERs), the estrogen receptor alpha (ERα) and the estrogen receptor beta (ERβ). [1] [2] [6] In one study, the EC 50 Tooltip half-maximal effective concentration value of estradiol for the human ERα was 50 pM (0.05 nM) and for the human ERβ was 200 pM (0.2 nM).
0.5 0.5 0.5: 1 h 1 h ... were 200-fold higher than estradiol levels with 2 mg/day oral ... have longer durations than free estradiol or less lipophilic ...
0.15 [5] 0.75 [5] μkat/L Male: 0.15 [5] 1 ... Levels of estradiol (the main estrogen), progesterone, ... Slightly less than osmolality: mOsm/L: Plasma volume ...
During pregnancy, levels of estradiol increase to very high concentrations that are as much as 100-fold normal levels. [138] [139] [140] In late pregnancy, the body produces and secretes approximately 100 mg of estrogens, including estradiol, estrone, and estriol, per day. [138]
Template: Plasma estrogen levels after a single dose of estradiol by different routes. Add languages. Add links. ... 0.5 0.5 0.5: 1 h 1 h 1 h 1 h +450 +250 +750 +75 ...