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  2. Ossification - Wikipedia

    en.wikipedia.org/wiki/Ossification

    Ossification. Bone is broken down by osteoclasts, and rebuilt by osteoblasts, both of which communicate through cytokine (TGF-β, IGF) signalling. Ossification (also called osteogenesis or bone mineralization) in bone remodeling is the process of laying down new bone material by cells named osteoblasts.

  3. Osteoclast - Wikipedia

    en.wikipedia.org/wiki/Osteoclast

    An osteoclast (from Ancient Greek ὀστέον (osteon) 'bone' and κλαστός (clastos) 'broken') is a type of bone cell that breaks down bone tissue. This function is critical in the maintenance, repair, and remodeling of bones of the vertebral skeleton. The osteoclast disassembles and digests the composite of hydrated protein and mineral ...

  4. Wolff's law - Wikipedia

    en.wikipedia.org/wiki/Wolff's_law

    Additionally, osteoprogenitor cells, which may differentiate into osteoblasts or osteoclasts, are also mechanosensors and will differentiate depending on the loading condition. [9] Computational models suggest that mechanical feedback loops can stably regulate bone remodeling by reorienting trabeculae in the direction of the mechanical loads. [10]

  5. Bone resorption - Wikipedia

    en.wikipedia.org/wiki/Bone_resorption

    Bone resorption is resorption of bone tissue, that is, the process by which osteoclasts break down the tissue in bones [1] and release the minerals, resulting in a transfer of calcium from bone tissue to the blood. [2] The osteoclasts are multi-nucleated cells that contain numerous mitochondria and lysosomes. These are the cells responsible for ...

  6. Olecranon - Wikipedia

    en.wikipedia.org/wiki/Olecranon

    Olecranon. The olecranon (/ oʊˈlɛkrənɒn /, from Greek olene 'elbow' and kranon 'head'), is a large, thick, curved bony process on the proximal, posterior end of the ulna. It forms the protruding part of the elbow and is opposite to the cubital fossa or elbow pit (trochlear notch). The olecranon serves as a lever for the extensor muscles ...

  7. Osteocyte - Wikipedia

    en.wikipedia.org/wiki/Osteocyte

    Anatomical terms of microanatomy. [edit on Wikidata] An osteocyte, an oblate shaped type of bone cell with dendritic processes, is the most commonly found cell in mature bone. It can live as long as the organism itself. [1] The adult human body has about 42 billion of them. [2] Osteocytes do not divide and have an average half life of 25 years.

  8. Bone - Wikipedia

    en.wikipedia.org/wiki/Bone

    A bone is a rigid organ [1] that constitutes part of the skeleton in most vertebrate animals. Bones protect the various other organs of the body, produce red and white blood cells, store minerals, provide structure and support for the body, and enable mobility. Bones come in a variety of shapes and sizes and have complex internal and external ...

  9. Osteoblast - Wikipedia

    en.wikipedia.org/wiki/Osteoblast

    Osteoclasts break down bone tissue, and along with osteoblasts and osteocytes form the structural components of bone. In the hollow within bones are many other cell types of the bone marrow . Components that are essential for osteoblast bone formation include mesenchymal stem cells (osteoblast precursor) and blood vessels that supply oxygen and ...