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Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects joints. [1] It typically results in warm, swollen, and painful joints. [1] Pain and stiffness often worsen following rest. [1] Most commonly, the wrist and hands are involved, with the same joints typically involved on both sides of the body. [1]
Osteoarthritis usually occurs as an individual ages and often affects the hips, knees, shoulders, and fingers. [5] Rheumatoid arthritis is an autoimmune disorder that often affects the hands and feet. [5] Other types of arthritis include gout, lupus, and septic arthritis. [3] [5] These are inflammatory based types of rheumatic disease. [2]
Rheumatism [2] / ˈ r uː m ə t ɪ z əm / or rheumatic disorders are conditions causing chronic, often intermittent pain affecting the joints or connective tissue. [3] Rheumatism does not designate any specific disorder, but covers at least 200 different conditions, including arthritis and "non-articular rheumatism", also known as "regional pain syndrome" or "soft tissue rheumatism".
The knee may become affected by almost any form of arthritis. [2] The word arthritis refers to inflammation of the joints. [3] [4] Types of arthritis include those related to wear and tear of cartilage, such as osteoarthritis, to those associated with inflammation resulting from an overactive immune system (such as rheumatoid arthritis). [5] [6]
As the disease progresses it can be seen in the knees, wrists, hips, and shoulders. This condition can affect and damage several other body systems such as the eyes, heart, lungs, and blood vessels. [7] Rheumatoid arthritis is a condition that cannot be cured but symptoms can be treated using certain medications alone or in conjunction.
The key clinical feature in JIA is persistent swelling of the affected joints. Any joint can be affected, but large joints such as the knee and ankle are most commonly involved. [6] Involvement of small joints of the hands and feet is more likely when many joints are affected ('polyarthritis'). Swollen joints may also feel warmer to touch.
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