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Recent studies have demonstrated that electrical stimulation of nerves leads to inhibitory input to the pain pathways at the spinal cord level. [7] PNS is most effective in the treatment of neuropathic pain (e.g., posttraumatic neuropathy, diabetic neuropathy) when the nerve lesion is distal to the site of stimulation.
Electrical brain stimulation was first used in the first half of the 19th century by pioneering researchers such as Luigi Rolando [citation needed] (1773–1831) and Pierre Flourens [citation needed] (1794–1867), to study the brain localization of function, following the discovery by Italian physician Luigi Galvani (1737–1798) that nerves and muscles were electrically excitable.
ECT is used, where possible, with informed consent [33] in treatment-resistant major depressive disorder, bipolar depression, treatment-resistant catatonia, prolonged or severe mania, and in conditions where "there is a need for rapid, definitive response because of the severity of a psychiatric or medical condition (e.g., when illness is ...
ECT can be used in the treatment for those with major depressive disorder, depressed bipolar disorder, manic bipolar disorder, schizophrenia, manic excitement and catatonia. [7] "Decision to conduct ECT therapy usually comes after there has been failure in other forms of treatment, including medication and psychotherapy". [7]
The mainstay of treatment for schizophrenia is an antipsychotic medication. [5] Most antipsychotics can take around 7 to 14 days to have their full effect. Medication may improve the positive symptoms of schizophrenia, and social and vocational functioning. [6]
1 Diana Perkins, a psychiatrist who has been running an early intervention program at the University of North Carolina for about 10 years, told me, “I used to treat clinical schizophrenia and I wasn’t expecting people to get better like this. With this kind of psychosis, it just didn’t happen.”
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