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Heart failure with reduced ejection fraction (HFrEF, hef-REF) is a form of heart failure in which the ejection fraction is reduced. [1] This is defined as a left ventricular ejection fraction (LVEF) of 40% or less. About half of heart failure patients have a reduced ejection fraction. [2]
HFrEF is associated with an ejection fraction less than 40%. [62] Heart failure with mildly reduced ejection fraction (HFmrEF), previously called "heart failure with mid-range ejection fraction", [63] is defined by an ejection fraction of 41–49%. [63] Heart failure with preserved ejection fraction (HFpEF): Synonyms no longer recommended ...
Heart failure with preserved ejection fraction (HFpEF) is a form of heart failure in which the ejection fraction – the percentage of the volume of blood ejected from the left ventricle with each heartbeat divided by the volume of blood when the left ventricle is maximally filled – is normal, defined as greater than 50%; [1] this may be measured by echocardiography or cardiac catheterization.
A heart which cannot pump sufficient blood to meet the body's requirements (i.e., heart failure) will often, but not invariably, have a reduced ventricular ejection fraction. [6] In heart failure, the difference between heart failure with a reduced ejection fraction, and heart failure with a preserved ejection fraction, is significant, because ...
XXB750 is an investigational drug developed by Novartis Pharmaceuticals, designed to treat resistant hypertension (rHTN) and heart failure with reduced ejection fraction (HFrEF). It functions as a natriuretic peptide receptor 1 (NPR1) agonist and is administered via subcutaneous injection.
heart failure: HFpEF: heart failure with preserved ejection fraction: HFrEF: heart failure with reduced ejection fraction HFM: hand, foot and mouth disease: HFMD: hand, foot and mouth disease: HFNC: high flow Nasal cannula: HFRS: hemorrhagic fever with renal syndrome HGB: hemoglobin: HGH Human Growth Hormone: HGSIL: high-grade squamous ...
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