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Pregabalin, sold under the brand name Lyrica among others, is an anticonvulsant, analgesic, and anxiolytic amino acid medication used to treat epilepsy, neuropathic pain, fibromyalgia, restless legs syndrome, opioid withdrawal, and generalized anxiety disorder (GAD). [13] [17] [18] Pregabalin also has antiallodynic properties.
[24] [25] Conversely, the oral bioavailability of pregabalin is greater than or equal to 90% across and beyond its entire clinical dose range (75 to 900 mg/day). [24] Food does not significantly influence the oral bioavailability of pregabalin. [24] Conversely, food increases the area-under-curve levels of gabapentin by about 10%. [24]
It was approved by the FDA in 2004 and marketed by Pfizer (which bought Parke-Davis) under the trade name Lyrica. [6] [10] Research has shown that the mechanism of the drug is more complicated than originally anticipated. [11] In addition to its effects on GABA-AT substrate behavior, pregabalin binds to calcium channels and blocks glutamate ...
First, the proposed tariffs will lead to the increase in prices of nearly every consumer product. Tariffs are a tax imposed by an importing country which is paid by the end customer.
The FDA on Thursday approved a new class of pain medication that provides an alternative to opioids. It will be sold under the brand name Journavx.
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