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Alka-Seltzer is an effervescent antacid and pain reliever owned by Bayer since 1978. First marketed by the Dr. Miles Medicine Company of Elkhart, Indiana , United States , Alka-Seltzer contains three active ingredients: aspirin (acetylsalicylic acid or ASA), sodium bicarbonate , and anhydrous citric acid . [ 1 ]
The US Food and Drug Administration recommends aspirin (or aspirin-containing products) should not be given to anyone under the age of 12 who has a fever, [188] and the UK National Health Service recommends children who are under 16 years of age should not take aspirin, unless it is on the advice of a doctor. [205]
The company is known for inventing products such as Alka-Selzer and One-A-Day vitamins. [1] Miles operated as an independent firm from 1884 until 1979 and as a wholly owned subsidiary of Bayer AG from 1979 until 1995. At the company's peak in the 1960s and 1970s, it employed 3,300 people and produced more than two dozen products. [2]
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Anatomy and physiology is different in infants and children than adults and vary with age, which produces normal ranges for electrocardiograms. [26] Capillary refill is used across the lifespan as a cardiovascular assessment parameter because it is a non-invasive, quick test to help determine blood flow to the tissues.
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