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  2. T cell - Wikipedia

    en.wikipedia.org/wiki/T_cell

    T cells are one of the important types of white blood cells of the immune system and play a central role in the adaptive immune response. T cells can be distinguished from other lymphocytes by the presence of a T-cell receptor (TCR) on their cell surface. T cells are born from hematopoietic stem cells, [1] found in the bone marrow.

  3. Tissue-resident memory T cell - Wikipedia

    en.wikipedia.org/wiki/Tissue-resident_memory_T_cell

    T RM cells have tissue residency-promoting transcriptional signature with features specific to individual tissues and features necessary for long-term survival in these tissues. [9] Skin T RM: T RM cells in the skin express cutaneous lymphocyte antigen (CLA) and CCR8 which are skin homing antigens. They have also higher expression of markers ...

  4. T memory stem cell - Wikipedia

    en.wikipedia.org/wiki/T_memory_stem_cell

    Longitudinal studies on T SCM dynamics in patients undergoing hematopoietic stem cell transplantation (HSCT) have shown that donor-derived T SCM cells were highly enriched early after HSCT, differentiated directly from Tn, and that Tn and T SCM cells (but not central memory or effector T cells) were able to reconstitute the entire heterogeneity of memory T cell subsets including T SCM cells. [6]

  5. Lymphopoiesis - Wikipedia

    en.wikipedia.org/wiki/Lymphopoiesis

    Early B cell development: from stem cell to immature B cell Transitional B cell development: from immature B cell to MZ B cell or mature FO B cell. A generally regarded valid map of B cell lymphopoiesis is as follows in sequence, in two parts with the first being in the bone marrow and the second in the spleen:. [18]

  6. Thymocyte - Wikipedia

    en.wikipedia.org/wiki/Thymocyte

    The purpose of thymocyte development is to produce mature T cells with a diverse array of functional T cell receptors, through the process of TCR gene rearrangement. Unlike most genes, which have a stable sequence in each cell which expresses them, the T cell receptor is made up of a series of alternative gene fragments. In order to create a ...

  7. Memory T cell - Wikipedia

    en.wikipedia.org/wiki/Memory_T_cell

    Antigen-specific memory T cells specific to viruses or other microbial molecules can be found in both central memory T cells (T CM) and effector memory T cells (T EM) subsets. . Although most information is currently based on observations in the cytotoxic T cells (CD8-positive) subset, similar populations appear to exist for both the helper T cells (CD4-positive) and the cytotoxic T ce

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