Ads
related to: what does elastin do in skin cancer cells recovery date after birth timelinecancer.osu.edu has been visited by 10K+ users in the past month
Search results
Results From The WOW.Com Content Network
Elastin-like polypeptides (ELPs) are synthetic biopolymers with potential applications in the fields of cancer therapy, tissue scaffolding, metal recovery, and protein purification. For cancer therapy, the addition of functional groups to ELPs can enable them to conjugate with cytotoxic drugs. [ 1 ]
Skin elastosis causes Condition Distinctive features Histopathology Actinic elastosis (most common, also called solar elastosis) Elastin replacing collagen fibers of the papillary dermis and reticular dermis: Elastosis perforans serpiginosa: Degenerated elastic fibers and transepidermal perforating canals (arrow in image points at one of them) [18]
Elastin is a protein encoded by the ELN gene in humans and several other animals. Elastin is a key component in the extracellular matrix of gnathostomes (jawed vertebrates). [ 5 ] It is highly elastic and present in connective tissue of the body to resume its shape after stretching or contracting. [ 6 ]
Timing is important to wound healing. Critically, the timing of wound re-epithelialization can decide the outcome of the healing. [11] If the epithelization of tissue over a denuded area is slow, a scar will form over many weeks, or months; [12] [13] If the epithelization of a wounded area is fast, the healing will result in regeneration.
Cutaneous squamous-cell carcinoma is the second-most common cancer of the skin (after basal-cell carcinoma, but more common than melanoma). It usually occurs in areas exposed to the sun. Sunlight exposure and immunosuppression are risk factors for SCC of the skin, with chronic sun exposure being the strongest environmental risk factor. [26]
Overexpression of the miR-655 mimic in the Panc1 cancer cell line upregulated the expression of E-cadherin and suppressed the migration and invasion of mesenchymal-like cancer cells. [76] The use of microRNA mimics to suppress EMT has expanded to other cancer cell lines and holds potential for clinical drug development. [74]
109901 Ensembl ENSG00000139610 ENSMUSG00000023031 UniProt Q9UNI1 Q91X79 RefSeq (mRNA) NM_001971 NM_033612 RefSeq (protein) NP_001962 NP_291090 Location (UCSC) Chr 12: 51.33 – 51.35 Mb Chr 15: 100.57 – 100.59 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Chymotrypsin-like elastase family member 1 (CELA1) also known as elastase-1 (ELA1) is an enzyme that in humans is encoded by ...
Actinic elastosis, also known as solar elastosis, is an accumulation of abnormal elastin (elastic tissue) in the dermis of the skin, [2] or in the conjunctiva of the eye, [3] which occurs as a result of the cumulative effects of prolonged and excessive sun exposure, a process known as photoaging.