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Lipinski's rule of five, also known as Pfizer's rule of five or simply the rule of five (RO5), is a rule of thumb to evaluate druglikeness or determine if a chemical compound with a certain pharmacological or biological activity has chemical properties and physical properties that would likely make it an orally active drug in humans.
Population research: Discovering the motivational drivers of target patient populations is commonly gathered through focus groups, and may involve caregivers and physicians. Site selection: Choosing the optimal recruiting sites for study participation may play a role in the type of patients that are recruited.
Snowball sampling is a recruitment method that employs research into participants' social networks to access specific populations. According to research mentioned in the paper written by Kath Browne, [20] using social networks to research is accessible. In this research, Kath Browne used social networks to research non-heterosexual women.
Gravimetric analysis describes a set of methods used in analytical chemistry for the quantitative determination of an analyte (the ion being analyzed) based on its mass. The principle of this type of analysis is that once an ion's mass has been determined as a unique compound, that known measurement can then be used to determine the same analyte's mass in a mixture, as long as the relative ...
As defined by nationwide consensus among scientists and educators, this literacy has two key parts. First, a literate person is defined, in language that echoes the above definition of scientific literacy. Second, a set of concepts are listed, organized into six to nine big ideas or essential principles.
A mobility shift assay is electrophoretic separation of a protein–DNA or protein–RNA mixture on a polyacrylamide or agarose gel for a short period (about 1.5-2 hr for a 15- to 20-cm gel). [4] The speed at which different molecules (and combinations thereof) move through the gel is determined by their size and charge, and to a lesser extent ...
The general expression Qualitative Analysis [...] refers to analyses in which substances are identified or classified on the basis of their chemical or physical properties, such as chemical reactivity, solubility, molecular weight, melting point, radioactivity properties (emission, absorption), mass spectra, nuclear half-life, etc. Quantitative Analysis refers to analyses in which the amount ...
Chemistry education research is typically carried out in situ using human subjects from secondary and post-secondary schools. Chemistry education research utilizes both quantitative and qualitative data collection methods. [12] [13] Quantitative methods typically involve collecting data that can then be analyzed using various statistical ...