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Blood oxygen saturation may be used for hypoxic hypoxia, but is generally meaningless in other forms of hypoxia. In hypoxic hypoxia 95–100% saturation is considered normal; 91–94% is considered mild and 86–90% moderate. Anything below 86% is considered severe. [8] Cerebral hypoxia refers to oxygen levels in brain tissue, not blood.
It has been found to increase oxygen consumption in the brain, apparently in connection to ATP metabolism, and increases the activity of adenylate kinase in rat brains. [26] [27] Piracetam, while in the brain, appears to increase the synthesis of cytochrome b5, [28] which is a part of the electron transport mechanism in mitochondria.
These drugs increase the permeability of the blood–brain barrier temporarily by increasing the osmotic pressure in the blood which loosens the tight junctions between the endothelial cells. By loosening the tight junctions normal injection of drugs through an [IV] can take place and be effective to enter the brain. [ 8 ]
As is the case for all antiepileptic drugs, it is advisable not to suddenly discontinue topiramate, as there is a theoretical risk of rebound seizures. Some studies have attributed loss of appetite and upper respiratory tract infection to topiramate, but studies have concluded these adverse events are not difficult to tolerate for most individuals.
The human body requires and regulates a very precise and specific balance of oxygen in the blood. Normal arterial blood oxygen saturation levels in humans are 96–100 percent. [1] If the level is below 90 percent, it is considered low and called hypoxemia. [2] Arterial blood oxygen levels below 80 percent may compromise organ function, such as ...
The therapy involves breathing pure oxygen in a chamber with above-normal air pressure. Some treatments are endorsed by medical experts, but not all. Hyperbaric oxygen therapy is touted as ...
Hypoxia can be due to external causes, when the breathing gas is hypoxic, or internal causes, such as reduced effectiveness of gas transfer in the lungs, reduced capacity of the blood to carry oxygen, compromised general or local perfusion, or inability of the affected tissues to extract oxygen from, or metabolically process, an adequate supply ...
Allergy medications may cause brain damage, increase dementia risk because of course they can, everything can. Alex Lasker. Updated July 14, 2016 at 10:50 PM.