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A 2024 systematic review of the literature found that chemoradiation with 5-FU and mitomycin C, as used in the Nigro Protocol, improves outcomes like colostomy-free survival in anal cancer patients compared to alternatives like cisplatin. However, it can lead to more severe side effects, especially blood-related toxicity. [7]
Intervention mapping [1] is a protocol for developing theory-based and evidence-based health promotion programs. Intervention Mapping describes the process of health promotion program planning in six steps: the needs assessment based on the PRECEDE-PROCEED model
Medical research for cancer begins much like research for any disease. In organized studies of new treatments for cancer, the pre-clinical development of drugs, devices, and techniques begins in laboratories, either with isolated cells or in small animals, most commonly rats or mice. In other cases, the proposed treatment for cancer is already ...
Superfood – a marketing term applied to certain foods with supposed health-giving properties. Cancer Research UK note that superfoods are often promoted as having an ability to prevent or cure diseases, including cancer; they caution, "a healthy, balanced and varied diet can help to reduce the risk of cancer but it is unlikely that any single ...
Nicholas James Gonzalez (December 28, 1947 – July 21, 2015) was a New York–based physician known for developing the Gonzalez regimen (or Gonzalez protocol), an alternative cancer treatment. [ 1 ] [ 2 ] [ 3 ] Gonzalez's treatments were based on his belief that pancreatic enzymes were the body's main defense against cancer and could be used ...
Most alternative cancer treatments have not been tested in proper clinical trials. Among studies that have been published, the quality is often poor. A 2006 review of 196 clinical trials that studied unconventional cancer treatments found a lack of early-phase testing, little rationale for dosing regimens, and poor statistical analyses. [11]
Hoxsey Therapy or Hoxsey Method is an alternative medical treatment promoted as a cure for cancer.The treatment consists of a caustic herbal paste for external cancers or a herbal mixture for "internal" cancers, combined with laxatives, douches, vitamin supplements, and dietary changes.
In medicine an intention-to-treat (ITT) analysis of the results of a randomized controlled trial is based on the initial treatment assignment and not on the treatment eventually received. ITT analysis is intended to avoid various misleading artifacts that can arise in intervention research such as non-random attrition of participants from the ...