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While the exact cause or causes are unknown, Crohn's disease seems to be due to a combination of environmental factors and genetic predisposition. [102] Crohn's is the first genetically complex disease in which the relationship between genetic risk factors and the immune system is understood in considerable detail. [ 103 ]
Crohn’s is an autoimmune disorder that causes inflammation and damage to the gastrointestinal (GI) tract, according to the U.S. Centers for Disease Control and Prevention.
Physicians tell the difference between Crohn's disease and UC by the location and nature of the inflammatory changes. Crohn's can affect any part of the gastrointestinal tract, from mouth to anus (skip lesions), although a majority of the cases start in the terminal ileum. Ulcerative colitis, in contrast, is restricted to the colon and the ...
In developed countries, 10–15% of adults experience gallstones. [4] Gallbladder and biliary-related diseases occurred in about 104 million people (1.6% of people) in 2013 and resulted in 106,000 deaths. [8] [9] Gallstones are more common among women than men and occur more commonly after the age of 40. [2]
Feeling overwhelmed by a Crohn’s disease diagnosis? Try these doctor-recommended first steps. You Just Found Out You Have Crohn's Disease—Here Are 6 Things Gastroenterologists Recommend You Do ...
It primarily causes abdominal pain, diarrhea (which may be bloody if inflammation is severe), vomiting (can be continuous), or weight loss, [1] [2] [3] but may also cause complications outside the gastrointestinal tract such as skin rashes, arthritis, inflammation of the eye, tiredness, and lack of concentration.
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