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Hepatitis E due to genotypes other than 1 and 2 is thought to be a zoonosis, in that animals are thought to be the primary reservoir; deer and swine have frequently been implicated. [61] Domestic animals have been reported as a reservoir for the hepatitis E virus, with some surveys showing infection rates exceeding 95% among domestic pigs. [62]
Age-standardised Death Rate (per 100,000) in 2017 ... Acute hepatitis E: 0.2: ... ~9.9% deaths of adults aged 40 to 69 years and ~7.8% adults aged 70 years or older ...
Acute hyperbilirubinemia is found in >70% of hepatitis E patients but chronic infection is scarce. [16] The transmission routes of hepatic viruses A and E are oral-faecal while that of hepatic viruses B, C and D are parenteral. [6] [15] [16] In general, conditions that increase risk of contracting hepatitis viruses infections include [3] [17]
Human infectious diseases may be characterized by their case fatality rate (CFR), the proportion of people diagnosed with a disease who die from it (cf. mortality rate).It should not be confused with the infection fatality rate (IFR), the estimated proportion of people infected by a disease-causing agent, including asymptomatic and undiagnosed infections, who die from the disease.
It affects predominantly young adults, causing acute hepatitis. [17] [134] In infected pregnant women, Hepatitis E infection can lead to fulminant hepatitis with third trimester mortality rates as high as 30%. [106] [134] Those with weakened immune systems, such as organ transplant recipients, are also susceptible. [134]
Hepatitis E is caused by the Hepatitis E virus (HEV), from the family Hepeviridae. It produces symptoms similar to hepatitis A , although it can take a fulminant course in some patients, particularly pregnant women (mortality rate about 20%); chronic infections may occur in immune-compromised patients.
― A Hepatitis A outbreak traced to a Beaver County restaurant 20 years ago may have led to many of the national food safety guidelines implemented in the last several years. ... “Chi-Chi’s ...
Hepatitis B: According to the World Health Organization, as of 2019 there are about 296 million people living with chronic hepatitis B, with 1.5 million new infections each year. In 2019, hepatitis B caused about 820,000 deaths, mostly from cirrhosis and hepatocellular carcinoma (primary liver cancer ). [ 23 ]