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Dakin's solution is a dilute solution of sodium hypochlorite (0.4% to 0.5%) and other stabilizing ingredients, traditionally used as an antiseptic, e.g. to cleanse wounds in order to prevent infection. [1] The preparation was for a time called also Carrel–Dakin solution or Carrel–Dakin fluid. [2]
Wound area covered in povidone-iodine. Gauze has also been applied. Povidone-iodine is a broad spectrum antiseptic for topical application in the treatment and prevention of wound infection. It may be used in first aid for minor cuts, burns, abrasions and blisters.
However systemic reviews in 2014, 2017 and 2018 concluded that more modern treatments, both with and without silver, show better results for wound healing and infection-prevention than silver sulfadiazine, [25] [26] [27] and therefore SSD is no longer generally recommended. [28] [29]
An antiseptic (Greek: ἀντί, romanized: anti, lit. 'against' [ 1 ] and σηπτικός , sēptikos , 'putrefactive' [ 2 ] ) is an antimicrobial substance or compound that is applied to living tissue to reduce the possibility of sepsis , infection , or putrefaction .
Products containing PHMB are used for inter-operative irrigation, pre- and post-surgery skin and mucous membrane disinfection, post-operative dressings, surgical and non-surgical wound dressings, surgical bath/hydrotherapy, chronic wounds like diabetic foot ulcer and burn wound management, routine antisepsis during minor incisions ...
[12] [13] [14] Its antiseptic properties were reported around 1875. [15] [16] [17] The compound was being used as a vaginal antiseptic by the late 1800s. [18] Clinical studies of boric acid for treatment of vaginal infections began being published in the late 1900s and early 2000s. [5]
Acriflavine (INN: acriflavinium chloride) is a topical antiseptic. It has the form of an orange or brown powder. It may be harmful in the eyes or if inhaled. It is a dye and it stains the skin and may irritate. The hydrochloride form is more irritating than the neutral form. It is derived from acridine.
Another Cochrane systematic review from 2010 concluded, "There is insufficient evidence to establish whether silver-containing dressings or topical agents promote wound healing or prevent wound infection". [9] Other reviews of the evidence have also concluded, "[the] quality of the trials was limited". [10]