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  2. Risk factors of schizophrenia - Wikipedia

    en.wikipedia.org/wiki/Risk_factors_of_schizophrenia

    Evidence suggests that it is the interaction between genes and the environment may be associated with the development of schizophrenia. [2] This is a complex process involving multiple environmental factors that have influence on a range of developmental periods that interact with a genetic susceptibility. [7]

  3. Schizophrenia - Wikipedia

    en.wikipedia.org/wiki/Schizophrenia

    The question of how schizophrenia could be primarily genetically influenced, given that people with schizophrenia have lower fertility rates, is a paradox. It is expected that genetic variants that increase the risk of schizophrenia would be selected against, due to their negative effects on reproductive fitness .

  4. Psychiatric genetics - Wikipedia

    en.wikipedia.org/wiki/Psychiatric_genetics

    If possible to test for schizophrenia before the symptoms develop, proactive interventions could be developed, or even preventative treatments. [7] In one study, 100% of patients with bipolar disorder indicated that they would probably take a genetic test to determine they were carrying a gene associated with the disorder, if such a test existed.

  5. Epigenetics of schizophrenia - Wikipedia

    en.wikipedia.org/wiki/Epigenetics_of_schizophrenia

    Schizophrenia is a debilitating and often misunderstood disorder that affects up to 1% of the world's population. [1] Although schizophrenia is a heavily studied disorder, it has remained largely impervious to scientific understanding; epigenetics offers a new avenue for research, understanding, and treatment.

  6. Evolution of schizophrenia - Wikipedia

    en.wikipedia.org/wiki/Evolution_of_Schizophrenia

    The self-domestication hypothesis for evolution of schizophrenia observes the importance our self-domesticated evolution, with emphasis on its contribution to the altered genetic development of the neural crest and our relaxed social cultural niche. Adaptations related these domesticated changes favored the emergence of complex cognitive ...

  7. Causes of schizophrenia - Wikipedia

    en.wikipedia.org/wiki/Causes_of_schizophrenia

    The causes of schizophrenia that underlie the development of schizophrenia, a psychiatric disorder, are complex and not clearly understood.A number of hypotheses including the dopamine hypothesis, and the glutamate hypothesis have been put forward in an attempt to explain the link between altered brain function and the symptoms and development of schizophrenia.

  8. Imprinted brain hypothesis - Wikipedia

    en.wikipedia.org/wiki/Imprinted_brain_hypothesis

    Proponents of the imprinted brain hypothesis argue that since it is uncertain if a woman's other and future children have and will have the same father, as well as the father generally having lower parental investment, it may be in the father's reproductive interest for his child to use more of the mother's resources than other children, while it may be in the mother's interest for a child to ...

  9. Glutamate hypothesis of schizophrenia - Wikipedia

    en.wikipedia.org/wiki/Glutamate_hypothesis_of...

    The hypothesis was initially based on a set of clinical, neuropathological, and, later, genetic findings pointing at a hypofunction of glutamatergic signaling via NMDA receptors. While thought to be more proximal to the root causes of schizophrenia , it does not negate the dopamine hypothesis , and the two may be ultimately brought together by ...