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English: Illustration of va Mimivirus, one of the greatest known viruses.It is called mimicking microbe reflecting its large size and apparent Gram-staining properties. (SVG format version of the infographic / illustration of mimivirus, based upon various web-based sources, including giantvirus.org and wikipedia)
Schematic drawing of a virion of genus Mimivirus (cross section and side view) showing filaments ("hairs") and stargate (downside) Mimivirus is a genus of giant viruses, in the family Mimiviridae. It is believed that Amoeba serve as their natural hosts. [2] [3]. It also refers to a group of phylogenetically related large viruses. [4]
The first member of this family, Mimivirus, was discovered in 2003, [6] and the first complete genome sequence was published in 2004. [7] However, the mimivirus Cafeteria roenbergensis virus [8] was isolated and partially characterized in 1995, [9] although the host was misidentified at the time, and the virus was designated BV-PW1.
Diagram showing the proximity of gene content of five members of the family Mimiviridae [7] CeV’s genome has 473,558 bp and a low G-C content of 25%. It is predicted to have 512 ORFs. [6] CeV possess a large number of core genes like the major capsid protein and the DNA polymerase B close to the respective genes of PgV.
A diagram of CroV's genome, showing the functional categories of what the genome encodes for, when in the viral life the genes are expressed, the types of promoters, as well as the types of repeats. CroV is the sole member of the genus Cafeteriavirus in the family Mimiviridae within the proposed order Megavirales. [ 10 ]
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The first mimivirus (BV-PW1) was described in 1995, [15] but was not recognized as such until its sequenced genome was released as Cafeteria roenbergensis virus (CroV) in 2010. [16] Subsequently, the Giant Virus Acanthamoeba polyphaga Mimivirus was characterized [17] (which had been mistaken as a bacterium in 1993), [18] and then sequenced. [19]