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Targeted temperature management (TTM), previously known as therapeutic hypothermia or protective hypothermia, is an active treatment that tries to achieve and maintain a specific body temperature in a person for a specific duration of time in an effort to improve health outcomes during recovery after a period of stopped blood flow to the brain. [1]
Hypothermia reduces vasogenic oedema, haemorrhage and neutrophil infiltration after trauma. [31] The release of excitatory neurotransmitters is reduced, limiting intracellular calcium accumulation. [ 32 ] [ 33 ] [ 34 ] Free radical production is lessened, which protects cells and cellular organelles from oxidative damage during reperfusion. [ 35 ]
SGA predicts susceptibility to hypoglycemia, hypothermia, and polycythemia. [2] By definition, at least 10% of all newborns will be labeled SGA. All SGA babies should be watched for signs of failure to thrive, hypoglycemia and other health conditions.
778.2 Cold injury syndrome of newborn; 778.3 Other hypothermia of newborn; 778.4 Other disturbances of temperature regulation of newborn; 778.5 Other and unspecified edema of newborn; 778.6 Congenital hydrocele; 778.7 Breast engorgement in newborn; 778.8 Other specified conditions involving the integument of fetus and newborn
Hypothermia therapy is also sometimes termed hypothermic neural rescue therapy. Clinical trials are taking place to investigate the effectiveness of stem cell-based interventions, which are thought to have the potential to reduce mortality and improve the long-term development of newborn infants with neonatal encephalopathy.
Under the proposal, the ICD-9-CM code sets would be replaced with the ICD-10-CM code sets, effective October 1, 2013. On April 17, 2012, the Department of Health and Human Services (HHS) published a proposed rule that would delay the compliance date for the ICD-10-CM and PCS by 12 months-from October 1, 2013, to October 1, 2014. [4]
The ICD-10 Procedure Coding System (ICD-10-PCS) is a US system of medical classification used for procedural coding.The Centers for Medicare and Medicaid Services, the agency responsible for maintaining the inpatient procedure code set in the U.S., contracted with 3M Health Information Systems in 1995 to design and then develop a procedure classification system to replace Volume 3 of ICD-9-CM.
Since the syndrome is due to the accumulation of chloramphenicol, the signs and symptoms are dose related. [10] According to Kasten's review published in the Mayo Clinic Proceedings, a serum concentration of more than 50 μg/mL is a warning sign, [10] while Hammett-Stabler and John states that the common therapeutics peak level is 10-20 μg/mL and is expected to achieve after 0.5-1.5 hours of ...