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Substrate reduction therapy is FDA approved and there is at least one treatment available on the market. [10] Gene therapy aims to replace a missing protein in the body through the use of vectors, usually viral vectors. [11] In gene therapy, a gene encoding for a certain protein is inserted into a vector. [11]
Positive responses to treatment may indicate a better prognosis. A 2005 study by the Mayo Clinic noted that individuals with RA have a doubled risk of heart disease, [199] independent of other risk factors such as diabetes, excessive alcohol use, and elevated cholesterol, blood pressure and body mass index.
n/a Ensembl n/a n/a UniProt n a n/a RefSeq (mRNA) n/a n/a RefSeq (protein) n/a n/a Location (UCSC) n/a n/a PubMed search n/a n/a Wikidata View/Edit Human arachidonate 5-lipoxygenase Identifiers EC no. 1.13.11.34 CAS no. 80619-02-9 [permanent dead link ] Databases IntEnz IntEnz view BRENDA BRENDA entry ExPASy NiceZyme view KEGG KEGG entry MetaCyc metabolic pathway PRIAM profile PDB ...
Rheumatoid arthritis (RA) is an autoimmune disease that mainly affects an individual's joints, but can affect and cause problems in different tissues. [26] A study that used enzyme-linked immunosorbent assay (ELISA) to measure sCD58 (soluble form of CD58) in individuals with RA and normal controls (NC) to determine if there was a correlation ...
Rheumatoid arthritis is an autoimmune disorder that often affects the hands and feet. [5] Other types of arthritis include gout, lupus, and septic arthritis. [3] [5] These are inflammatory based types of rheumatic disease. [2] Early treatment for arthritis commonly includes resting the affected joint and conservative measures such as heating or ...
Celecoxib, sold under the brand name Celebrex among others, is a COX-2 inhibitor and nonsteroidal anti-inflammatory drug (NSAID). [7] It is used to treat the pain and inflammation in osteoarthritis, acute pain in adults, rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, painful menstruation, and juvenile rheumatoid arthritis. [7]
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