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Benznidazole is an antiparasitic medication used in the treatment of Chagas disease. [2] While it is highly effective in early disease, the effectiveness decreases in those who have long-term infection. [3] It is the first-line treatment given its moderate side effects compared to nifurtimox. [1] It is taken by mouth. [2] Side effects are ...
Chagas disease is managed using antiparasitic drugs to eliminate T. cruzi from the body, and symptomatic treatment to address the effects of the infection. [6] As of 2018, benznidazole and nifurtimox were the antiparasitic drugs of choice for treating Chagas disease, [2] though benznidazole is the only drug available in most of Latin America. [40]
Nifurtimox, sold under the brand name Lampit, is a medication used to treat Chagas disease and sleeping sickness. [2] [4] For sleeping sickness it is used together with eflornithine in nifurtimox-eflornithine combination treatment. [4] In Chagas disease it is a second-line option to benznidazole. [5] It is given by mouth. [2]
Antiprotozoals are used to treat protozoal infections, which include amebiasis, giardiasis, cryptosporidiosis, microsporidiosis, malaria, babesiosis, trypanosomiasis, Chagas disease, leishmaniasis, and toxoplasmosis. [6] Currently, many of the treatments for these infections are limited by their toxicity. [7]
The logo of the Drugs for Neglected Diseases initiative (DNDi) The Drugs for Neglected Diseases initiative (DNDi) is a collaborative, patients' needs-driven, non-profit drug research and development (R&D) organization that is developing new treatments for neglected diseases, notably leishmaniasis, sleeping sickness (human African trypanosomiasis, HAT), Chagas disease, [1] malaria, filarial ...
Including prebiotics (e.g. onions, leeks, garlic, oats and bananas) and fermented foods (like kimchi, miso, kefir or sauerkraut) in your daily diet promotes all-around gut health.
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