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Severe allergic reactions to anesthetic medications are rare and are usually attributable to factors other than the anesthetic. Neuromuscular blocking agents, natural rubber latex, and antibiotics are the most common causes of serious allergic reactions during surgery. [2] The mortality rate from these reactions ranges between 3-9%. [3]
Anesthetic risk factors include the use of volatile anesthetics, nitrous oxide (N 2 O), opioids, and longer duration of anesthesia. Patient factors that confer increased risk for PONV include female gender, obesity , age less than 16 years, past history of motion sickness or chemotherapy-induced nausea, high levels of preoperative anxiety , and ...
Those symptoms warrant a trip to the emergency department, Dr. Quinlan says. ... Reactions to Medication ... general anesthesia for surgery, and chemotherapy medications are more likely to cause ...
Signs and symptoms will vary depending on the type of allergy. Type 1 reactions have a rapid onset of symptoms which include swelling, redness, rashes, itchiness, chest tightness, breathing problems. A Type 4 reaction has a delayed onset of symptoms and is usually localized to the site of injection.
Anaphylaxis is a severe allergic reaction of rapid onset affecting many body systems. [ 5 ] [ 8 ] It is due to the release of inflammatory mediators and cytokines from mast cells and basophils , typically due to an immunologic reaction but sometimes non-immunologic mechanism.
Postanesthetic shivering is one of the leading causes of discomfort in patients recovering from general anesthesia. It usually results due to the anesthetic inhibiting the body's thermoregulatory capability, although cutaneous vasodilation (triggered by post-operative pain) may also be a causative factor.
Diphenhydramine is a first-generation antihistamine used to treat several conditions including allergic symptoms and itchiness, the common cold, insomnia, motion sickness, and extrapyramidal symptoms. [19] [20] Diphenhydramine also has local anesthetic properties, and has been used as such in people allergic to common local anesthetics such as ...
Abdominal pain, nausea, vomiting, oral allergy syndrome, urticaria, neck or facial swelling, severe asthma symptoms, exercise induced anaphylaxis, potentially fatal anaphylactic shocks [6] Higher risk of provoking life-threatening reactions compared to most other food allergies. Celery seeds and celeriac are more allergenic than celery stalks.