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Vascular dementia can sometimes be triggered by cerebral amyloid angiopathy, which involves accumulation of amyloid beta plaques in the walls of the cerebral arteries, leading to breakdown and rupture of the vessels. [2] [5] Since amyloid plaques are a characteristic feature of Alzheimer's disease, vascular dementia may occur as a consequence ...
Age effects on grey matter density in the posterior temporal cortex appear more predominantly in the left versus right hemisphere, and were confined to posterior language cortices. Certain language functions such as word retrieval and production were found to be located to more anterior language cortices, and deteriorate as a function of age.
Cerebellar degeneration continues to carry a considerable burden on the health of the world population, as well as on health agencies and governing bodies across the globe. Cerebellum-related disorders generally transpire in individuals between the ages of 45 to 65 years, however the age of symptomatic onset differs in accordance with the ...
The loss of cholinergic neurons noted in the limbic system and cerebral cortex, is a key feature in the progression of Alzheimer's. [39] The 1991 amyloid hypothesis postulated that extracellular amyloid beta (Aβ) deposits are the fundamental cause of the disease.
Some common indicators used to indicate health include total fertility rate, infant mortality rate, life expectancy, crude birth and death rate.As of 2017, Singapore has a Total Fertility Rate of 1.16 [5] children born per woman, an Infant Mortality rate of 2.2 deaths per 1000 live births, [6] Crude Birth Rate of 8.9 births per 1000 people [7] and a Death Rate of 3 deaths per 1000 inhabitants. [8]
Micrograph showing cortical pseudolaminar necrosis. H&E-LFB stain.. Cortical pseudolaminar necrosis, also known as cortical laminar necrosis and simply laminar necrosis, is the death of cells in the cerebral cortex of the brain in a band-like pattern, [1] with a relative preservation of cells immediately adjacent to the meninges.
Corticobasal degeneration (CBD) is a rare neurodegenerative disease involving the cerebral cortex and the basal ganglia. [1] CBD symptoms typically begin in people from 50 to 70 years of age, and typical survival before death is eight years.
Damage to the cerebral cortex may lead to aphasia or confusion and damage to the cerebellum may lead to lack of motor movement. [5] Stroke presentations which are particularly suggestive of a watershed stroke include bilateral visual loss, stupor, and weakness of the proximal limbs, sparing the face, hands and feet.