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Tamsulosin, sold under the brand names including Flomax and Contiflo, is a medication used to treat symptomatic benign prostatic hyperplasia (BPH) and chronic prostatitis and to help with the passage of kidney stones. [6] [7] [8] The evidence for benefit with a kidney stone is better when the stone is larger. [8] Tamsulosin is taken by mouth. [6]
On the first day, they'd have 100 mg in their system; their body would clear 10 mg, leaving 90 mg. On the second day, the patient would have 190 mg in total; their body would clear 19 mg, leaving 171 mg. On the third day, they'd be up to 271 mg total; their body would clear 27 mg, leaving 244 mg.
Adverse effects from finasteride are rare in men with already enlarged prostates; [12] however, some men experience sexual dysfunction, depression, and breast enlargement. [13] [14] In some men, sexual dysfunction may persist after stopping the medication. [15] [16] It may also hide the early symptoms of certain forms of prostate cancer. [14]
A floating system is a system where it floats on gastric fluids due to low density. The density of the gastric fluids is about 1 g/mL; thus, the drug/tablet administered must have a smaller density. The buoyancy will allow the system to float to the top of the stomach and release at a slower rate without worry of excreting it.
In the general population, chronic pelvic pain syndrome occurs in about 0.5% of men in a given year. [88] It is found in men of any age, with the peak incidence in men aged 35–45 years. [89] However, the overall prevalence of symptoms suggestive of CP/CPPS is 6.3%. [90]
The osmotic-controlled release oral delivery system (OROS) is an advanced controlled release oral drug delivery system in the form of a rigid tablet with a semi-permeable outer membrane and one or more small laser drilled holes in it.
A uroflometer for measuring urine flow. Urine flow rate or urinary flow rate is the volumetric flow rate of urine during urination.It is a measure of the quantity of urine excreted in a specified period of time (per second or per minute).
Median IELT was independent of condom use. Median IELT decreased with age (18–30: 6.5 minutes, 31–50: 5.4 minutes, above 51: 4.3 minutes). Median IELT for all participants was 5.4 minutes. Median IELT varied significantly by individual with 14% of men under 3:20 and 26% of men over 10:00.