Search results
Results From The WOW.Com Content Network
Defensive behaviour and predatory behaviours appear normal in these knockout mice, [14] but there is evidence that social motivation or awareness is reduced. [15] The AVPR1B antagonist, SSR149415, has been shown to have anti-aggressive actions in hamsters [ 16 ] and anti-depressant- and anxiety (anxiolytic)-like behaviors in rats. [ 17 ]
Sometimes measuring blood levels of ADH (a synonym for vasopressin) during this test is also necessary. [ citation needed ] If there is no change in the water loss despite fluid deprivation, desmopressin may be administered to distinguish between the two types of diabetes insipidus which are central & nephrogenic diabetes insipidus.
The actions of vasopressin are mediated by stimulation of tissue-specific G protein-coupled receptors (GPCRs) called vasopressin receptors that are classified into the V 1 (V 1A), V 2, and V 3 (V 1B) receptor subtypes. [1]
Also, unlike vasopressin 1b receptor and oxytocin knockout mice, AVPR1A knockout mice have a normal Bruce effect (appropriate failure of pregnancy in presence of novel male). [ 17 ] Although activation of AVPR1A is a major mediator of anxiogenesis in males, it is not in females.
The willingness of the female rats to access males was considered a direct measure of the females' levels of sexual motivation. An increase in vasopressin has been observed in female rats which have just given birth. Vasopressin is associated with aggressive and hostile behaviours, and is postulated to decrease sexual motivation in females.
551 11998 Ensembl ENSG00000101200 ENSMUSG00000037727 UniProt P01185 P35455 RefSeq (mRNA) NM_000490 NM_009732 RefSeq (protein) NP_000481 NP_033862 Location (UCSC) Chr 20: 3.08 – 3.08 Mb Chr 2: 130.42 – 130.42 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse The arginine vasopressin (AVP) gene is a gene whose product is proteolytically cleaved to produce vasopressin (also known as ...
Dysfunctions of the PVN can cause hypersomnia in mice. [2] In humans, the dysfunction of the PVN and the other nuclei around it can lead to drowsiness for up to 20 hours per day. [3] The PVN is thought to mediate many diverse functions through different hormones, including osmoregulation, appetite, wakefulness, and the response of the body to ...
This may also be called standard range. In contrast, optimal (health) range or therapeutic target is a reference range or limit that is based on concentrations or levels that are associated with optimal health or minimal risk of related complications and diseases. For most substances presented, the optimal levels are the ones normally found in ...