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The kidney is a very complex organ and mathematical modelling has been used to better understand kidney function at several scales, including fluid uptake and secretion. [ 35 ] [ 36 ] Clinical significance
A simple means of estimating renal function is to measure pH, blood urea nitrogen, creatinine, and basic electrolytes (including sodium, potassium, chloride, and bicarbonate). As the kidney is the most important organ in controlling these values, any derangement in these values could suggest renal impairment.
Kidney disease results from kidney damage and subsequent decline in kidney function. ... The human body has 78 organs and each one performs a variety of important functions. While it's possible ...
The kidney has many functions, which a well-functioning kidney realizes by filtering blood in a process known as glomerular filtration. A major measure of kidney function is the glomerular filtration rate (GFR). The glomerular filtration rate is the flow rate of filtered fluid through the kidney.
In a healthy human, the kidney receives between 12 and 30% of cardiac output, but it averages about 20% or about 1.25 L/min. The basic structural and functional unit of the kidney is the nephron . Its chief function is to regulate the concentration of water and soluble substances like sodium by filtering the blood , reabsorbing what is needed ...
That said, “it's important to note, if you have kidney disease or reduced kidney function, you should either not take metformin or take this drug under supervision by a healthcare professional ...