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The exact mechanism of action of silicone gel sheeting has not been fully studied. Currently, many proposed mechanisms explain the efficacy of such treatment, including the occlusion and hydration effect, increased body surface temperature, polarized electric charge, immunological effects, etc. [9] The occlusion and hydration effect is the most studied mechanism of action.
A keloid scar is benign and not contagious, but sometimes accompanied by severe itchiness, pain, [2] and changes in texture. In severe cases, it can affect movement of skin. In the United States, keloid scars are seen 15 times more frequently in people of sub-Saharan African descent than in people of European descent. [3]
Therapies for AKN may include topical antibiotics, topical or intralesional corticosteroids, and laser hair removal. Recommended modifications to shaving habits include liberal use of shaving cream , avoidance of stretching the skin while shaving, and use of a single-blade razor rather than a razor with multiple blades.
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A map of the process of Indian Removal, 1830–1838. Oklahoma is depicted in light yellow-green. In 1830, a group of Indian nations collectively referred to as the "Five Civilized Tribes" (the Cherokee, Chickasaw, Choctaw, Muscogee, and Seminole nations), were living autonomously in what would later be termed the American Deep South.
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