Search results
Results From The WOW.Com Content Network
Neural tube defects (NTDs) are a group of birth defects in which an opening in the spine or cranium remains from early in human development. In the third week of pregnancy called gastrulation , specialized cells on the dorsal side of the embryo begin to change shape and form the neural tube .
Rachischisis is a neural tube defect characterised by a complete or severe defect in the spine. The defect can be located anywhere from the cervical region to the sacrum, or through the entire length of the spine. Typical defects are clefts or splits that open the spine to the exterior environment.
Ideally, the neural tube, i.e. the developing spinal cord, will close before the full development of the fat and muscle formed by the mesoderm. In lipomyelomeningocele and other spinal lipomas, however, the mesoderm forming the fat will migrate into the neural tube. The mesoderm and neural tube will continue to develop until a tumor of fat is ...
Women who have already had a baby with spina bifida or other type of neural tube defect, or are taking anticonvulsant medication, should take a higher dose of 4–5 mg/day. [69] However, the daily requirement of folate and the recommended folate blood levels to prevent neural tube defects are not well established. [59]
Encephalocele is a neural tube defect characterized by sac-like protrusions of the brain and the membranes that cover it through openings in the skull.These defects are caused by failure of the neural tube to close completely during fetal development.
Anencephaly is the absence of a major portion of the brain, skull, and scalp that occurs during embryonic development. [1] It is a cephalic disorder that results from a neural tube defect that occurs when the rostral (head) end of the neural tube fails to close, usually between the 23rd and 26th day following conception. [2]
The MOMS Trial was a clinical trial that studied treatment of a birth defect called myelomeningocele, which is the most severe form of spina bifida. The study looked at prenatal (before birth) and postnatal (after birth) surgery to repair this defect. The first major phase concluded that prenatal surgery had strong, long-term benefits and some ...
In 1972, R. G. Sutcliffe and D. J. H. Brock found that higher amniotic alpha-fetoprotein levels were associated with neural tube defects. [6] In 1972, ultrasound-guided amniocenteses began replacing free-handed taps following J. Bang and A. Northeved's initiative to employ ultrasound technology to improve amniocentesis.