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Deaths. 59,800 (2015) [ 6 ] Melanoma is the most dangerous type of skin cancer; it develops from the melanin -producing cells known as melanocytes. [ 1 ] It typically occurs in the skin, but may rarely occur in the mouth, intestines, or eye (uveal melanoma). [ 1 ][ 2 ] In women, melanomas most commonly occur on the legs; while in men, on the ...
Breslow's depth. In medicine, Breslow's depth was used as a prognostic factor in melanoma of the skin. It is a description of how deeply tumor cells have invaded. Currently, the standard Breslow's depth has been replaced by the AJCC depth, in the AJCC staging system of melanoma. Originally, Breslow's depth was divided into 5 stages.
Skin cancer is the most commonly diagnosed form of cancer in humans. [11] [12] [13] There are three main types of skin cancers: basal-cell skin cancer (BCC), squamous-cell skin cancer (SCC) and melanoma. [1] The first two, along with a number of less common skin cancers, are known as nonmelanoma skin cancer (NMSC).
Five anatomical levels are recognized, and higher levels have worsening prognostic implications. These levels are: [ 1 ] Level 1: Melanoma confined to the epidermis (melanoma in situ) Level 2: Invasion into the papillary dermis. Level 3: Invasion to the junction of the papillary and reticular dermis. Level 4: Invasion into the reticular dermis.
Treatments for melanoma result in higher survival rate than people may expect. But a key to this is early detection. Currently there is a 99% five-year survival rate for early detected melanoma.
Superficial spreading melanoma (SSM) is a type of skin cancer that typically starts as an irregularly edged dark spot typically on sun-exposed part of the body. [2][3] The colour may be variable with dark, light and reddish shades; occasionally no color at all. [2] It typically grows in diameter before spreading to deeper tissue, forming a bump ...
Amelanotic melanoma is a type of skin cancer in which the cells do not make any melanin. [1]: 696 [2] They can be pink, red, purple or of normal skin color, and are therefore difficult to diagnose correctly. They can occur anywhere on the body, just as a typical melanoma can. Often, amelanotic melanomas are mistaken for benign lesions ...
Uveal melanoma. A sensation of flashes or specks of dust (floaters); growing dark spot on the iris; change in the shape of the pupil; poor or blurry vision in one eye; loss of peripheral vision in one eye. For choroid: choroidal tumors, especially choroidal nevus, metastatic tumors, choroidal hemangioma, and osteoma; hemorrhagic conditions like ...
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