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Immunodeficiency, also known as immunocompromisation, is a state in which the immune system 's ability to fight infectious diseases and cancer is compromised or entirely absent. Most cases are acquired ("secondary") due to extrinsic factors that affect the patient's immune system. Examples of these extrinsic factors include HIV infection and ...
Hypogammaglobulinemia. Hypogammaglobulinemia is an immune system disorder in which not enough gamma globulins are produced in the blood (thus hypo- + gamma + globulin + -emia). This results in a lower antibody count, which impairs the immune system, increasing risk of infection. Hypogammaglobulinemia may result from a variety of primary genetic ...
Immune disorder. An immune disorder is a dysfunction of the immune system. [1] These disorders can be characterized in several different ways: According to the International Union of Immunological Societies, more than 150 primary immunodeficiency diseases (PIDs) have been characterized. [2] However, the number of acquired immunodeficiencies ...
Roseola, also known as sixth disease, is an infectious disease caused by certain types of human herpes viruses. [2] Most infections occur before the age of three. [1] Symptoms vary from absent to the classic presentation of a fever of rapid onset followed by a rash. [1][2] The fever generally lasts for three to five days, while the rash is ...
Immunosuppression is a reduction of the activation or efficacy of the immune system. Some portions of the immune system itself have immunosuppressive effects on other parts of the immune system, and immunosuppression may occur as an adverse reaction to treatment of other conditions. [1][2] In general, deliberately induced immunosuppression is ...
Sophie Hambleton is a British physician who is Professor of Paediatrics and Immunology at Newcastle University. She is a clinical paediatric immunologist at the Great North Children's Hospital, which specialises in treating children with immunodeficiencies. Hambleton looks to understand the cellular and molecular basis of immune system errors.
The adaptive immune system, also known as the acquired immune system, or specific immune system is a subsystem of the immune system that is composed of specialized, systemic cells and processes that eliminate pathogens or prevent their growth. The acquired immune system is one of the two main immunity strategies found in vertebrates (the other ...
Autoinflammatory diseases. Autoinflammatory diseases (AIDs) are a group of rare disorders caused by dysfunction of the innate immune system. These responses are characterized by periodic or chronic systemic inflammation, usually without the involvement of adaptive immunity. Autoinflammatory diseases are a separate class from autoimmune diseases ...
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