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Early treatment of an ectopic pregnancy with methotrexate is a viable alternative to surgical treatment [56] which was developed in the 1980s. [57] If administered early in the pregnancy, methotrexate terminates the growth of the developing embryo; the developing embryo may then be either resorbed by the woman's body or pass with a menstrual ...
Methotrexate, formerly known as amethopterin, is a chemotherapy agent and immune-system suppressant. [4] It is used to treat cancer , autoimmune diseases , and ectopic pregnancies . [ 4 ] Types of cancers it is used for include breast cancer , leukemia , lung cancer , lymphoma , gestational trophoblastic disease , and osteosarcoma . [ 4 ]
Ectopic pregnancy is treated with methotrexate therapy or surgery. Typically, an intramuscular injection of 50 mg per m^2 of methotrexate is given followed by close monitoring of b-hCG levels 4 and 7 days after injection. B-hCG levels should decrease by at least 15% between those two timepoints. [26]
A rarely used drug combination for uterine pregnancies is methotrexate-misoprostol, which is typically reserved for ectopic pregnancies. [41] Methotrexate is given either orally or intramuscularly, followed by vaginal misoprostol 3–5 days later. [22] The methotrexate combination is available through 63 days.
Ovarian pregnancies have been successfully treated with methotrexate [10] since it was introduced in the management of ectopic pregnancy in 1988. [11] An ovarian pregnancy can develop together with a normal intrauterine pregnancy; such a heterotopic pregnancy will call for expert management as not to endanger the intrauterine pregnancy.
Hasci said she has a client, Hope, who was misdiagnosed with an ectopic pregnancy in Alamogordo. A doctor gave her methotrexate to terminate the pregnancy. The result was that the child, now 3 ...
Methotrexate is used as a treatment of ectopic pregnancies and studies have shown that the drug does not affect future fertility treatments. There were multiple studies that looked at the number of oocytes that were retrieved before and after the treatment with methotrexate and found that there was not a significant difference. [3]
Methotrexate, which causes abortion, is ACOG's current standard of care for medical management of tubal ectopic pregnancy. Catholic directives prohibiting methotrexate are ignored by hospitals because they are too far out of step with current practice to survive malpractice lawsuits. [ 30 ]