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[35] [34] Gynecomastia and breast pain improved or resolved upon discontinuation in 70 and 90% of patients, respectively. [34] Resolution of breast symptoms was dependent on duration of bicalutamide therapy, with resolution rates ranging from 29% with >18 months of treatment to 64% for <6 months of treatment. [34]
Gynecomastia can be normal in newborn male babies due to exposure to estrogen from the mother, in adolescent boys going through puberty, in older men over the age of 50, and in obese men. [4] Most occurrences of gynecomastia do not require diagnostic tests.
Mammoplasia can be an effect or side effect of various drugs, including estrogens, [2] [13] antiandrogens such as spironolactone, [14] cyproterone acetate, [15] bicalutamide, [16] [17] and finasteride, [18] [19] growth hormone, [20] [21] and drugs that elevate prolactin levels such as D 2 receptor antagonists like antipsychotics (e.g ...
In women, estrogens can additionally cause vaginal bleeding, vaginal discharge, and anovulation, whereas in men, estrogens can additionally cause gynecomastia (male breast development), feminization, demasculinization, sexual dysfunction (reduced libido and erectile dysfunction), hypogonadism, testicular atrophy, and infertility.
In addition to symptoms of hypogonadism and sexual dysfunction, hyperprolactinemia can cause breast changes such as breast pain, breast enlargement, gynecomastia, and galactorrhea. [ 55 ] [ 71 ] [ 72 ] Galactorrhea secondary to hyperprolactinemia is very common in premenopausal women (80%) but more uncommon in individuals with low estrogen ...
PHOTO: Semaglutide (GLP-1) weight-loss drug Wegovy, made by pharmaceutical company Novo Nordisk is seen on Oct. 16, 2024. (James Manning/PA Images via Getty Images)
One of the challenges is that symptoms of stroke in women have a number of overlapping symptoms with migraine. For example, both severe migraine and stroke may cause vision changes and dizziness.
Estrogenic side effects such as gynecomastia and fluid retention can also occur. [1] Case reports of gynecomastia exist. [ 21 ] [ 22 ] As with other 17α-alkylated steroids, methandienone poses a risk of hepatotoxicity and use over extended periods of time can result in liver damage without appropriate precautions.