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Alfred Sturtevant's Drosophila melanogaster genetic linkage map: This was the first successful gene mapping work and provides important evidence for the chromosome theory of inheritance. The map shows the relative positions of allelic characteristics on the second Drosophila chromosome.
The Bithorax complex (BX-C) is one of two Drosophila melanogaster homeotic gene complexes, located on the right arm of chromosome 3. [1] It is responsible for the differentiation of the posterior two-thirds (posterior thorax and each abdominal segment) of the fly by the regulation of three genes within the complex: Ultrabithorax (Ubx ...
There are many possible products of this gene, which function as transcription factors. Ubx is used in the specification of serially homologous structures, and is used at many levels of developmental hierarchies. In Drosophila melanogaster it is expressed in the third thoracic (T3) and first abdominal (A1) segments and represses wing formation ...
Homeobox (Hox) gene expression in Drosophila melanogaster. Drosophila melanogaster is an important model for understanding body plan generation and evolution. The general principles of Hox gene function and logic elucidated in flies will apply to all bilaterian organisms, including humans. Drosophila, like all insects, has eight Hox genes ...
FlyBase is an online bioinformatics database and the primary repository of genetic and molecular data for the insect family Drosophilidae. [1] For the most extensively studied species and model organism, Drosophila melanogaster, a wide range of data are presented in different formats.
Balancer chromosomes were first used in the fruit fly by Hermann Muller, who pioneered the use of radiation for organismal mutagenesis. [2]In the modern usage of balancer chromosomes, random mutations are first induced by exposing living organisms with otherwise normal chromosomes to substances which cause DNA damage; in flies and nematodes, this usually occurs by feeding larvae ethyl ...
One species of Drosophila in particular, Drosophila melanogaster, has been heavily used in research in genetics and is a common model organism in developmental biology. The terms "fruit fly" and " Drosophila " are often used synonymously with D. melanogaster in modern biological literature.
Homeotic selector gene complexes in the fruit fly Drosophila melanogaster. One of the most commonly studied model organisms in regards to homeotic genes is the fruit fly Drosophila melanogaster. Its homeotic Hox genes occur in either the Antennapedia complex (ANT-C) or the Bithorax complex (BX-C) discovered by Edward B. Lewis. [10]