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Trade names in other countries include Dimedrol, Daedalon, Nytol, and Vivinox. It is also available as a generic medication . Procter & Gamble markets an over-the-counter formulation of diphenhydramine as a sleep aid under the brand ZzzQuil.
Together with scopolamine, it was the main ingredient in Sominex, Nytol, and Sleep-Eze. It also provided the sedative component of Excedrin PM. [2] All of these products were reformulated in the late 1970s [3] when methapyrilene was demonstrated to cause liver cancer in rats when given chronically. [4]
All medications within the NyQuil imprint contain sedating antihistamines, hypnotics, and/or alcohol; they are intended to be taken before sleep. Its daytime counterpart is antihistamine-free DayQuil, formulated to avoid drowsiness. NyQuil is also used as a sleep aid. [1] NyQuil was first marketed in the United States in 1966. [2] [3]
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