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In the 1980s, the European Union began harmonising regulatory requirements. In 1989, Europe, Japan, and the United States began creating plans for harmonisation. The International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH) was created in April 1990 at a meeting in Brussels.
Eating a variety of foods that contain potassium is the best way to get an adequate amount. Foods with high sources of potassium include kiwifruit, orange juice, potatoes, coconut, avocados, apricots, parsnips and turnips, although many other fruits, vegetables, legumes, and meats contain potassium. Common foods very high in potassium: [34]
With stability testing, pharmaceutical industry inspects the quality of drug substances and drug products as per the guidelines outlined by US Food and Drug Administration and International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use to make sure that they retained the quality over the period of time.
In food products, potassium hydroxide acts as a food thickener, pH control agent and food stabilizer. The FDA considers it generally safe as a direct food ingredient when used in accordance with Good Manufacturing Practices. [22] It is known in the E number system as E525.
Potassium sorbate is the potassium salt of sorbic acid, chemical formula CH 3 CH=CH−CH=CH−CO 2 K. It is a white salt that is very soluble in water (58.2% at 20 °C). It is primarily used as a food preservative (E number 202). [4] Potassium sorbate is effective in a variety of applications including food, wine, and personal-care products.
Potassium-40 is the largest source of natural radioactivity in animals including humans. A 70 kg human body contains about 140 g of potassium, hence about 140g × 0.0117% ≈ 16.4 mg of 40 K; [ 7 ] whose decay produces about 3850 [ 8 ] to 4300 disintegrations per second ( becquerel ) continuously throughout the life of an adult person (and ...
Potassium permanganate can be used to oxidize cocaine paste to purify it and increase its stability. This led to the Drug Enforcement Administration launching Operation Purple in 2000, with the goal of monitoring the world supply of potassium permanganate; however, potassium permanganate derivatives and substitutes were soon used thereafter to ...
Potassium ascorbate is a compound with formula KC 6 H 7 O 6. It is the potassium salt of ascorbic acid and a mineral ascorbate. As a food additive, it has E number E303, INS number 303. Although it is not a permitted food additive in the UK, USA and the EU, [2] [3] it is approved for use in Australia and New Zealand. [4]