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The Framingham Risk Score is a sex-specific algorithm used to estimate the 10-year cardiovascular risk of an individual. The Framingham Risk Score was first developed based on data obtained from the Framingham Heart Study, to estimate the 10-year risk of developing coronary heart disease. [1]
Hypocholesterolemia is the presence of abnormally low (hypo-) levels of cholesterol in the blood (-emia). A defect in the body's production of cholesterol can lead to adverse consequences as well. Cholesterol is an essential component of mammalian cell membranes and is required to establish proper membrane permeability and fluidity.
Likelihood Ratio: An example "test" is that the physical exam finding of bulging flanks has a positive likelihood ratio of 2.0 for ascites. Estimated change in probability: Based on table above, a likelihood ratio of 2.0 corresponds to an approximately +15% increase in probability.
The hazard ratio would be 2, indicating a higher hazard of death from the treatment. To illustrate how hazard ratio is linked to projected risk: in a population where the incidence of a disease is 10% by age 65 (eg: Dementia [1] [2]), a hazard ratio of 4.42 [3] (eg: Aripiprazole medication) results in an expected incidence of 37.3% by age 65. [4]
Cholesterol synthesis appears to occur mostly at night, [140] so statins with short half-lives are usually taken at night to maximize their effect. Studies have shown greater LDL and total cholesterol reductions in the short-acting simvastatin taken at night rather than the morning, [141] [142] but have shown no difference in the long-acting ...
Psyllium husk after processing Plantago afra, a member of the plant genus from which psyllium can be derived. Psyllium (/ ˈ s ɪ l i əm /), or ispaghula (/ ˌ ɪ s p ə ˈ ɡ uː l ə /), is the common name used for several members of the plant genus Plantago whose seeds are used commercially for the production of mucilage.